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IBS News

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  2. PLoS One. 2021 Jun 11;16(6):e0252930. doi: 10.1371/journal.pone.0252930. eCollection 2021. ABSTRACT BACKGROUND: Irritable bowel syndrome (IBS) is a pathologic condition characterized by changes in gut microbiome composition, low-grade inflammation, and disruption of intestinal wall permeability. The interaction between the gut microbiome and the disease manifestation remains unclear. The changing of tight junction proteins and cytokines expression throughout the gastrointestinal tract in IBS patients has not been studied yet. AIM OF THE STUDY: To assess the changes of gut microbiome compositio
  3. Front Pediatr. 2021 May 25;9:646686. doi: 10.3389/fped.2021.646686. eCollection 2021. ABSTRACT Introduction: Mind body techniques such as meditation improve symptoms in children and adults with IBS. Typical courses, however, are lengthy and difficult to administer. We report our experience with a short course of Preksha Dhyana (PD), a child-friendly focused meditation with yoga. Method: Physicians deliver focused meditation while medical assistants taught yoga. Three sessions were administered biweekly with recommendations for daily practice. Pain severity Likert scores were compared with a tr
  4. Minerva Med. 2021 Jun 11. doi: 10.23736/S0026-4806.21.07015-4. Online ahead of print. ABSTRACT BACKGROUND: Probiotics have been evaluated in multiple clinical trials on irritable bowel syndrome (IBS). However, in real-life long-term compliance could be low. Our study is single-center, observational and prospective, aiming both to evaluate the adherence to prescription of probiotic therapy in real-life and to identify factors able to influence adherence to therapy. METHODS: Fifty patients diagnosed with IBS according to Rome IV and receiving a clinical prescription of a multistrain probiotic pr
  5. Aliment Pharmacol Ther. 2021 Jun 11. doi: 10.1111/apt.16437. Online ahead of print. ABSTRACT BACKGROUND: Although bloating is a highly prevalent and troublesome symptom in irritable bowel syndrome with constipation (IBS-C), treatment is empirical with no specific guidelines for its management. AIM: To conduct a pairwise and network meta-analysis, using a frequentist approach, of Food and Drug Administration-licensed drugs for IBS-C comparing their efficacy for abdominal bloating as a specific endpoint. METHODS: We searched the medical literature through December 2020 to identify randomised con
  6. Last week
  7. Eur Rev Med Pharmacol Sci. 2021 May;25(10):3752-3761. doi: 10.26355/eurrev_202105_25943. ABSTRACT OBJECTIVE: Diet, visceral sensitivity, and psychological distress play an important role in Irritable Bowel Syndrome (IBS). This study focused on the relation between IBS severity, foods, visceral sensitivity, and anxiety/depression. PATIENTS AND METHODS: Patients with IBS were investigated through (1) IBS-symptoms severity score (SSS), (2) self-reported food intolerance, (3) visceral sensitivity index (VSI), and (4) Hospital Anxiety and Depression Scale (HADS). Seventy-seven patients agreed to pa
  8. We love our #GastroPsych community! https://twitter.com/DrvanTilburg/status/1402674936708321286 (Feed generated with FetchRSS) View the full article
  9. Is Your Poop Healthy? Check This Clinical Chart To Find Out. HuffPost Everyone poops, but it’s still something a lot of us have an awfully hard time talking about. (Unless you’re my 6-year-old and 3-year-old, who cannot talk about poop enough, it turns out.) But it’s unfortunate that poop talk tends to make adults squeamish, because our stool can offer some powerful clues about what’s going on inside our guts — and even more broadly within our bodies. And doctors really do wish people would lean into it. View the full article
  10. J Gastroenterol Hepatol. 2021 Jun 9. doi: 10.1111/jgh.15573. Online ahead of print. ABSTRACT BACKGROUND AND AIM: Previous studies have shown a reduction of gastrointestinal symptoms in irritable bowel syndrome (IBS) patients following a low FODMAP diet (LFD). It remains unknown, which disorders of gut-brain interaction (DGBI) patients, would benefit most from LFD. We aimed to analyze LFD response regarding a preceding nutrient challenge test (NCT). METHODS: Data of 110 consecutive DGBI patients undergoing NCT and LFD between 08/2015-2018 were analyzed retrospectively. LFD response was assessed
  11. J Med Internet Res. 2021 Jun 9;23(6):e26867. doi: 10.2196/26867. ABSTRACT BACKGROUND: Adolescents with irritable bowel syndrome (IBS) are increasingly seeking and sharing information about their symptoms in web-based health care forums. Their posts and those from their parents contain critical insights that can be used by patients, physicians, and caregivers to manage IBS symptoms. OBJECTIVE: The aim of this study is to examine the posts from adolescent patients and their parents in a health forum, IBS Group, to better understand the key challenges, concerns, and issues of interest to young pa
  12. Therap Adv Gastroenterol. 2021 May 30;14:17562848211020570. doi: 10.1177/17562848211020570. eCollection 2021. ABSTRACT BACKGROUND: Irritable bowel syndrome with diarrhoea (IBS-D) is a frequent problem associated with a significant socioeconomic implication. Increased gut permeability is an important pathophysiological mechanism. A medical device containing xyloglucan (XG), pea protein and tannins (PPT) from grape-seed extract, and xylo-oligosaccharides (XOS) has proven restoration of intestinal barrier function. Our objective was to evaluate the efficacy and safety of treatment with the medica
  13. Glob Pediatr Health. 2021 May 31;8:2333794X211022265. doi: 10.1177/2333794X211022265. eCollection 2021. ABSTRACT Functional gastrointestinal disorders are characterized by absence of anatomical and biochemical alterations, and are diagnosed and classified based on symptomatology. We aim to explore the prevalence of functional abdominal pain disorders and Functional constipation using Rome IV criteria. An online questionnaire was distributed randomly via social media targeting the general population of the western region of Saudi Arabia. Parents who have at least 1 child in the age group 3 to 1
  14. Small study finds in #IBS high somatization associated with impaired small intestinal permeability. https://pubmed.ncbi.nlm.nih.gov/34022802/ (Feed generated with FetchRSS) View the full article
  15. Front Endocrinol (Lausanne). 2021 May 19;12:684096. doi: 10.3389/fendo.2021.684096. eCollection 2021. ABSTRACT Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder that is more common in females. Despite its high global incidence, the disease mechanism is still unclear and therapeutic options remain limited. The sexual dimorphism in IBS incidence suggests that sex steroids play a role in disease onset and symptoms severity. This review considers sex steroids and their involvement in IBS symptoms and the underlying disease mechanisms. Estrogens and androgens play important r
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  17. One GI PhD student to another: please share this survey: IBS impacts on stress & health-related QOL. This research is being conducted by @AidaBenitezRexach for her program at Walden U. Open to adults 18-65 in the US. https://www.surveymonkey.com/r/M7FTLKJ @RomeFoundation @IFFGD @IBSpatient (Feed generated with FetchRSS) View the full article
  18. Eur Eat Disord Rev. 2021 Jun 4. doi: 10.1002/erv.2847. Online ahead of print. ABSTRACT OBJECTIVES: The prevalence of eating disorders is rising worldwide. The low body weight in anorexia nervosa as well as the increase in body mass index due to binge eating disorder are contributing to a strikingly high morbidity and mortality. In a similar pattern, the prevalence and burden of the disease of functional gastrointestinal disorders such as functional dyspepsia and irritable bowel syndrome is increasing. As gastrointestinal complaints are commonly reported by patients with eating disorders, the q
  19. J Educ Health Promot. 2021 Feb 27;10:50. doi: 10.4103/jehp.jehp_812_20. eCollection 2021. ABSTRACT BACKGROUND: Irritable bowel syndrome (IBS) is one of the most common gastrointestinal diseases, and obsessive-compulsive disorder (OCD) is one of the main causes of this disease. The present study was aimed to investigate the prevalence of OCD in patients with IBS. MATERIALS AND METHODS: The present research is a cross-sectional survey study. The research sample included 120 patients with IBS who referred to Imam Reza Hospital and gastrointestinal clinics in Kermanshah (Iran) in the 3 months of A
  20. Dig Liver Dis. 2021 May 31:S1590-8658(21)00247-4. doi: 10.1016/j.dld.2021.05.004. Online ahead of print. ABSTRACT BACKGROUND: The low FODMAP diet (LFD) is effective in managing irritable bowel syndrome (IBS) in the short term. This study assessed the long-term effect of the LFD on symptoms, nutritional composition and socialising. METHODS: Patients with IBS who received dietetic-led LFD advice were approached at long term follow up (>6 months post LFD advice) from six centres across the United Kingdom. Participants completed questionnaires assessing gastrointestinal symptoms, adherence, nut
  21. SARS-CoV-2 impacts brain-gut axis long-term Healio SARS-CoV-2 may have a lasting impact on the brain-gut axis, according to a presentation at Digestive Disease Week. “It is known that bacterial, protozoa and viral infections of the GI tract represent a risk factor for the development of functional GI disorders like irritable bowel syndrome and functional dyspepsia, as well as chronic fatigue and other extra-intestinal symptoms like somatoform disorders,” Daniele Noviello, MD, University of Milan, said. “In February 2020, a SARS-CoV-2 outbreak occurred in Italy with extreme severity
  22. Gut Microbes. 2021 Jan-Dec;13(1):1-16. doi: 10.1080/19490976.2021.1927635. ABSTRACT Dysbiosis of the gut microbiome has been correlated with irritable bowel syndrome (IBS). Fecal microbiota transplantation (FMT) is being explored as a therapeutic option. Little is known of the mechanisms of engraftment of microbes following FMT and whether the engraftment of certain microbes correlate with clinical improvement in IBS. Microbiome data, from a previously reported placebo-controlled trial of treatment of IBS with FMT or placebo capsules, were used to investigate microbial engraftment 15 days, 1,
  23. Functional gastrointestinal and somatoform symptoms five months after SARS‐CoV‐2 infection: A controlled cohort study Wiley Abstract Background Gastrointestinal infections represent a risk factor for functional gastrointestinal and somatoform extraintestinal disorders. We investigated the prevalence and relative risk (RR) of gastrointestinal and somatoform symptoms 5 months after SARS-CoV-2 infection compared with a control cohort. Methods One hundred and sixty-four SARS-CoV-2 infected patients and 183 controls responded to an online questionnaire about symptoms and s
  24. RT @wileyfoodsci: Irritable bowel syndrome (IBS) affects 5.7% of the general population. This mini-review in Neurogastroenterology & Motility discusses evidence of food #supplements & diet as treatment options for people with #IBS. 👉 http://ow.ly/B6Ff50EEbvm 👥 @EiriniDimidi @ProfWhelan (Feed generated with FetchRSS) View the full article
  25. Womens Midlife Health. 2021 May 31;7(1):4. doi: 10.1186/s40695-021-00064-5. ABSTRACT Midlife women between the ages of 40 and 65 years have reported multiple challenges due to menopausal, developmental, and situational transitions from younger to older adulthood. During the midlife period, many women seek health care for gastrointestinal symptoms and irritable bowel syndrome (IBS). Multiple factors including stress, poor sleep, diet, and physical inactivity may contribute to IBS or gastrointestinal symptoms in midlife women. As such, a comprehensive assessment and treatment approach is needed
  26. RT @NMGastro: Tiffany H Taft, PsyD (@DrTiffTaft), discusses avoidant restrictive food intake disorders in GI patients on a recent episode of GI Insights. Listen now: https://reachmd.com/programs/gi-insights/avoidant-restrictive-food-intake-disorders-in-gi-patients/12228/ (Feed generated with FetchRSS) View the full article
  27. Front Cell Infect Microbiol. 2021 May 12;11:524851. doi: 10.3389/fcimb.2021.524851. eCollection 2021. ABSTRACT INTRODUCTION: Interactions between the gut microbiota and enteroendocrine cells play important role in irritable bowel syndrome (IBS). Reduced stem cell densities and their differentiation into enteroendocrine cells may cause abnormal densities of the duodenal enteroendocrine cells in IBS patients. MATERIALS AND METHODS: We aimed to investigate the effects of fecal microbiota transplantation (FMT) on stem cell differentiation into enteroendocrine cells as detected by neurogenin 3, ste
  28. Dig Liver Dis. 2021 May 27:S1590-8658(21)00207-3. doi: 10.1016/j.dld.2021.04.022. Online ahead of print. ABSTRACT AIMS: To compare both the faecal bile acids (BAs) and the levels of two bile acid receptors, Takeda G protein-coupled receptor 5 (TGR5) and vitamin D receptor (VDR), in the colonic mucosa between patients with irritable bowel syndrome with predominant diarrhea (IBS-D) and healthy controls, and explore the correlations among clinical characteristics, bile acid receptors expression, and BAs. METHODS: The severity of abdominal pain and diarrhoea was assessed in IBS-D patients using va
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