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IBS News

Showing topics posted by Health Reporter and posted in for the last 365 days.

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  1. Yesterday
  2. CRJ Podcast: Treatment of a Bleeding Rectal Varix Using an Over-the-Scope Clip (16:20) Sergio @SanchezLunaMD discusses use of an over-the-scope clip to manage bleeding from a rectal varix refractory to mgmt w/ endoscopic banding w/ @RobertoSimonsMD ▶️ http://bit.ly/2R2H1a1 (Feed generated with FetchRSS) View the full article
  3. RT @helenbmurray: Some patients with chronic #constipation have #Eatingdisorder symptoms that maintain their GI symptoms. We found #anxiety around GI symptoms may be a key culprit in fueling the fire. @drkylestaller @RomeGastroPsych #GastroPsych @aedweb #EDECRs https://twitter.com/MassGeneralMDs/status/1217771017994719232 (Feed generated with FetchRSS) View the full article
  4. Many Dr. Schär products are also low #FODMAP diet ready too! #IBS https://twitter.com/Schar_UK/status/1218212660610830343 (Feed generated with FetchRSS) View the full article
  5. Last week
  6. RT @Rainmaker1973: Darwinian gastronomy. We evolved to like spices because they have antimicrobial properties, thus, reducing food poisoning, especially in hot climates https://buff.ly/2NYjyCj (Feed generated with FetchRSS) View the full article
  7. 6 Clues You're Full of Stool and What to Do About It U.S. News & World ReportView the full article
  8. January: IBS trial | News University of BristolView the full article
  9. Foods to eat with IBS: a new review updates the latest scientific evidence Gut Microbiota for HealthView the full article
  10. Probiotics: Don't Buy the Online Hype WebMDView the full article
  11. RT @AprilHackert: Consider your client population before prescribing a specific 'diet' @eatrightPRO @KateScarlata_RD #FODMAP #neverstoplearning #RDN #BHNFamily (Feed generated with FetchRSS) View the full article
  12. RT @SharonPalmerRD: Learn how to eat a #LowFODMAP diet to manage #IBS, even if you eat a #plantbased, #vegan, #vegetarian, or flexitarian diet, thanks to these tips from expert #dietitian @KateScarlata_RD https://sharonpalmer.com/2016-04-19-eating-for-ibs-on-a-plantbased-diet-with-kate-scarlata-rdn/ (Feed generated with FetchRSS) View the full article
  13. One-in-four adults fit Rome IV criteria for functional bowel disorders HealioView the full article
  14. Updated criteria cut the prevalence of #IBS in half, according to research published in @AGA_Gastro https://www.healio.com/gastroenterology/irritable-bowel-syndrome/news/online/%7B95a9e00c-fd14-400b-b8e8-4b2e835c222e%7D/one-in-four-adults-fit-rome-iv-criteria-for-functional-bowel-disorders?utm_medium=social&utm_source=twitter&utm_campaign=scheduledpost (Feed generated with FetchRSS) View the full article
  15. Debating Diets: What is the low-FODMAP diet? Baylor College of Medicine NewsView the full article
  16. Decreased expression of microRNA-510 in intestinal tissue contributes to post-infectious irritable bowel syndrome via targeting PRDX1. Am J Transl Res. 2019;11(12):7385-7397 Authors: Zhang Y, Wu X, Wu J, Li S, Han S, Lin Z, Ding S, Jia X, Gong W Abstract OBJECTIVE: Post-infectious irritable bowel syndrome (PI-IBS) is a common functional gastrointestinal (GI) disorder that occurs after acute GI infection. Recent studies showed that microRNAs were involved in the occurrence and development of IBS. Here, we elaborated the role of miR-510 in the occurrence of PI-IBS and analyzed its mechanism. METHODS: We detected the expressions of miR-510 and PRDX1 in colonic mucosal tissues by qRT-PCR, Western blot and immunohistochemistry. Furthermore, we transfected Caco-2 cells with miR-510 mimic, anti-miR-510, si-PRDX1, and control, then evaluated the cell viability and apoptosis by CCK8 assay and flow cytometry, assessed expression levels of PRDX1 by qRT-PCR and Western blot analysis, and pro-inflammatory cytokines by qRT-PCR and ELISA. RESULTS: MiR-510 expression was downregulated and negatively correlated with TNF-α, whereas PRDX1 expression was upregulated in PI-IBS colonic mucosal tissues. LPS at concentrations of 5 and 10 μg/ml can significantly induce inflammatory injury in Caco-2 cells. MiR-510 overexpression aggravated the injury induced by LPS, as reflected by increased cell viability, decreased apoptosis, and less production of pro-inflammatory cytokines. miR-510 mimic transfection in cells significantly suppressed the mRNA and protein expression levels of PRDX1. Furthermore, the inflammatory injury induced by LPS was exacerbated by upregulating PRDX1 expression when miR-510 was knocked down. CONCLUSION: MiR-510 downregulation in intestinal tissue might contribute to PI-IBS via targeting PRDX1. The results of this study will not only enrich the pathogenesis of PI-IBS but also make us understand the biological activity of miR-510 and provide important experimental basis for PI-IBS clinical treatment targeting miR-510. PMID: 31934286 [PubMed] View the full article
  17. Efficacy of Tenapanor in Treating Patients With Irritable Bowel Syndrome With Constipation: A 12-Week, Placebo-Controlled Phase 3 Trial (T3MPO-1). Am J Gastroenterol. 2020 Jan 13;: Authors: Chey WD, Lembo AJ, Rosenbaum DP Abstract OBJECTIVES: Tenapanor is a first-in-class, minimally absorbed, small-molecule inhibitor of the gastrointestinal sodium/hydrogen exchanger isoform 3. This phase 3 trial assessed the efficacy and safety of tenapanor 50 mg b.i.d. for the treatment of patients with constipation-predominant irritable bowel syndrome (IBS-C). METHODS: In this phase 3, double-blind study (ClinicalTrials.gov identifier NCT02621892), patients with IBS-C were randomized to tenapanor 50 mg b.i.d. or placebo b.i.d. for 12 weeks followed by a 4-week randomized withdrawal period. The primary efficacy variable was the proportion of patients who reported a reduction in average weekly worst abdominal pain of ≥30.0% and an increase of ≥1 complete spontaneous bowel movement from baseline, both in the same week, for ≥6 weeks of the 12-week treatment period. RESULTS: Of the 629 randomized patients with IBS-C, 606 (96.3%) were included in the intention-to-treat analysis set (tenapanor: n = 307; placebo: n = 299) and 533 (84.7%) completed the 12-week treatment period. In the intention-to-treat analysis set (mean age 45 years, 81.4% women), a significantly greater proportion of patients treated with tenapanor met the primary endpoint than patients treated with placebo (27.0% vs 18.7%, P = 0.020). Abdominal symptoms and global symptoms of IBS also improved with tenapanor (P < 0.05 vs placebo). Diarrhea was the most commonly reported adverse event, resulting in study drug discontinuation in 6.5% and 0.7% of patients receiving tenapanor and placebo, respectively, during the 12-week treatment period. DISCUSSION: Tenapanor 50 mg b.i.d. improved IBS-C symptoms and was generally well tolerated, offering a potential new treatment option for patients with IBS-C. PMID: 31934897 [PubMed - as supplied by publisher] View the full article
  18. GI peeps, join is on this convo! Follow thread with #TuesdayNightIBS Give your thoughts on patient case. Retweet. Many minds working together can offer help & hope 4 #IBS patients! @RomeGastroPsych @RomeFoundation @DrTiffTaft @LindaNguyenMD @ibsimpact @KateScarlata_RD https://twitter.com/TuesdayNightIBS/status/1217220071463976960 (Feed generated with FetchRSS) View the full article
  19. RT @TuesdayNightIBS: #TuesdayNightIBS Family support is an important part of the treatment for #FGiD #IBS https://twitter.com/john_damianos/status/1217226534228021249 (Feed generated with FetchRSS) View the full article
  20. RT @john_damianos: @TuesdayNightIBS Validation should go hand in hand w normalization. Explain that what she is experiencing is common in #IBS, so she is not alone. Fam meeting good bc husband will need education to understand what IBS is to best support wife. (1/2) #TuesdayNightIBS (Feed generated with FetchRSS) View the full article
  21. RT @john_damianos: @TuesdayNightIBS Validation from both home and care team are important 1st step in treatment. Without these, treatment (medical, behavioral, etc) is set up to fail. This patient would certainly benefit from #gastropsych in conjunction with any medical treatments. 2/2 #TuesdayNightIBS (Feed generated with FetchRSS) View the full article
  22. #TuesdayNightIBS https://twitter.com/john_damianos/status/1217221911253540866 (Feed generated with FetchRSS) View the full article
  23. Ibsrela improves abdominal symptoms in IBS-C HealioView the full article
  24. Related ArticlesLaparoscopic treatment of a pericaecal internal hernia. J Minim Access Surg. 2020 Jan 09;: Authors: Iriarte F, Buero A, Pirchi DE, Nardi WS, Irribarra MM Abstract We present the case of a pericaecal hernia treated successfully with a laparoscopic approach and full recovery after surgery. A 53-year-old female patient with a personal history of depression, osteoporosis and irritable bowel syndrome consulted to the emergency department for abdominal pain and distension in the last 12 h, associated with one episode of vomit and diminished frequency in the passage of stools. The right abdomen was tender to palpation, and blood work revealed no leucocytosis. A computed tomography scan showed small bowel loops distended and displaced to the right parietocolic recess, lateral to the ascending colon. Exploratory laparoscopy was performed confirming the presence of small bowel loops incarcerated in the paracaecal fossa. These ones were reduced with gentle manoeuvres, and the peritoneal folds incised to prevent recurrence. The patient was started on an oral diet 2 days after surgery and discharged home on the 3rd post-operative day. PMID: 31929229 [PubMed - as supplied by publisher] View the full article
  25. Related ArticlesCourse of the Diverticular Disease: What is changing? J Gastrointestin Liver Dis. 2020 Jan 08;28 suppl.1:11-16 Authors: Milosavljeviĉ T, Brandimarte G, Stollman N, Barbara G, Lahat A, Scarpignato C, Lanas A, Papa V, Tursi A, Nardone G Abstract In this session several critical issues in diverticular disease were considered, including "It is Symptomatic Diverticular Disease or Irritable Bowel Syndrome?", "What do determine evolution to diverticulitis, bowel habits alteration or inflammation?", and "Prevention of acute diverticulitis: Is it at all possible?". The first talking compared symptoms and laboratory findings between Symptomatic Uncomplicated Diverticular Disease (SUDD) and Irritable Bowel Syndrome (IBS). Although both disease share some symptoms, and although IBS can occur in patients having diverticulosis, SUDD and IBS can be differentiate using a combination of symptoms and laboratory tools. The second talking debated what are the most important risk factors for the evolution towards acute diverticulitis. Current data seem to exclude a significant role of bowel habits alteration, while inflammation seems to have a stronger role, especially in causing acute diverticulitis recurrence. The third talking analyzed about the acute diverticulitis prevention. Primary prevention seem to be little better when using mesalazine, while no definite conclusion can be drawn about the use of fiber and rifaximin. About the secondary prevention, no drugs can be currently advised due to lacking of definite results. At the same time, surgery should be advised on case-by-case basis. PMID: 31930229 [PubMed - in process] View the full article
  26. Is Something in Your Diet Screwing With Your Stomach? Here's How an Elimination Diet Could Help Discover MagazineView the full article
  27. Low #fodmap made easy with many new products on the market including @FodyFoods @GetEpicured read more: 👇🏼 https://twitter.com/todaysdietitian/status/1216841312567287808 (Feed generated with FetchRSS) View the full article
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