IBS Newsfeed

Endometriosis & Misdiagnosis: What You Need to Know NYU Langone Health Imagine experiencing debilitating pelvic pain for a decade, only to be told repeatedly that it’s just period cramps or anxiety. This is the reality for many women with endometriosis. An estimated 1 in 10 women of reproductive age have endometriosis, yet the average time from first symptoms to diagnosis is seven to 10 years. For many women, those years are spent seeing multiple doctors, receiving multiple misdiagnoses, and experiencing pain that affects work, relationships, and quality of life. And many women endure the added emotional toll of unexplained infertility. The long diagnostic delays ar…

J Pediatr Gastroenterol Nutr. 2026 Mar 23. doi: 10.1002/jpn3.70402. Online ahead of print. ABSTRACT OBJECTIVES: Dysbiosis due to early-life antibiotics may contribute to the development of functional gastrointestinal disorders (FGIDs). This follow-up study of a birth cohort primarily investigates the association between antibiotic treatment in the first week of life and the presence of FGIDs at 9-12 years. Secondarily, it examines whether a history of infantile colic or current food allergy is associated with FGIDs. METHODS: A prospective observational birth cohort of 436 term-born infants was followed up at the age of 9-12 years; 151 received intravenous antibiotics in t…

Turk J Gastroenterol. 2025 Nov 25;36(Suppl 2):S1-S38. doi: 10.5152/tjg.2025.101125. ABSTRACT some have been found to be ineffective or not cost-effective. Marked discrepancies in the availability and formulation of antispasmodic agents across countries-ranging from the limitation to only fundamental compounds in regions such as the United States to the mar-keting of diverse combination products elsewhere-have generated considerable ambiguity and debate within the field. Meta-analyses show varying results on the efficacy of antispasmodics, indicating the need for further analysis. This article aims to evaluate the effec-tiveness of antispasmodic drugs in relieving symptoms…

Ann Gastroenterol. 2026 Mar-Apr;39(2):174-183. doi: 10.20524/aog.2026.1044. Epub 2026 Feb 12. ABSTRACT Schoolchildren nowadays encounter multiple challenges within the teaching process. Learning disabilities (LD) are characterized as complex conditions that affect academic achievement and cognitive performance. LD are typically linked to neurodevelopmental and genetic factors. However, emerging evidence suggests they may be associated with gastrointestinal (GI) pathologies, including celiac disease, inflammatory bowel disease, irritable bowel syndrome, gastroesophageal reflux disease and Helicobacter pylori infection. The aforementioned GI disorders have been (indirectly)…

Am J Gastroenterol. 2026 Mar 20. doi: 10.14309/ajg.0000000000004001. Online ahead of print. ABSTRACT INTRODUCTION: Irritable bowel syndrome (IBS) is a disorder of gut-brain interaction which negatively affects patients' quality of life. It has been hypothesized that changes in gut microbiota composition and function evoked by antibiotic use represent a trigger for IBS development. This systematic review and meta-analysis aims to assess the incidence of IBS following antibiotic use. METHODS: Medline, Embase, and Scopus, along with relevant conference abstracts and citation tracking were searched up to June 15th, 2025. Studies that reported new diagnoses of IBS in patients …

Indian J Gastroenterol. 2026 Mar 19. doi: 10.1007/s12664-026-01972-y. Online ahead of print. ABSTRACT BACKGROUND: Bile acid malabsorption (BAM) is often missed in patients with chronic diarrhea as diagnostic tests are technically challenging and not available widely. Quantitative estimation of fecal bile acids (FBA) in a single stool sample has been reported recently for the diagnosis of BAM and may be easily applied. METHODS: We performed a pilot observational cross-sectional study to estimate the optimal FBA cut-point for the diagnosis of BAM, using the IDK® Bile Acid test, an enzymatic spectrophotometry-based assay for measuring total stool bile acids. We estimated FBA…

Patients Take Center Stage for World IBS Day 2026 World IBS Day Champions" Lead the Global Charge to Break Stigma and Foster Community TORONTO, March 18, 2026 /PRNewswire/ -- On April 19th, the global community will unite for World IBS Day 2026, a day dedicated to the millions of individuals navigating the daily challenges of Irritable Bowel Syndrome (IBS). This year's theme, "Champions Raise Awareness about IBS," shifts the spotlight directly onto the patients, transforming a silent struggle into a powerful, collective voice. VIsit worldibsday.org Putting a Face to the Condition IBS is a chronic gastrointestinal disorder characterized by debilitating symptoms like abdom…

Psychiatry Investig. 2026 Mar;23(3):345-352. doi: 10.30773/pi.2025.0366. Epub 2026 Mar 6. ABSTRACT OBJECTIVE: This study aimed to estimate the proportion meeting Rome III criteria for functional gastrointestinal disorders (FGIDs) and examine associations with suicide ideation (Beck Scale for Suicide Ideation, BSS), depression (Center for Epidemiological Studies-Depression Scale for Children, CES-DC), anxiety (Screen for Child Anxiety Related Emotional Disorders, SCARED), and perceived stress (Perceived Stress Scale, PSS) in child and adolescent psychiatric outpatients, including subgroup analyses by irritable bowel syndrome (IBS), functional constipation (FC), and subtype…

Med Ultrason. 2026 Mar 2. doi: 10.11152/mu-4592. Online ahead of print. ABSTRACT AIM: Patients with diarrhea-predominant irritable bowel syndrome (IBS-D) who present with symptom exacerbation [defined by a high IBS-Symptom Severity Scale (IBS-SSS)] may have increased fecal calprotectin (FC). Intestinal ultrasound (IUS) is used to measure bowel wall thickness (BWT). The aim of our study was to measure BWT in IBS-D patients, ulcerative colitis (UC) and healthy controls (HC), and compare BWT, IBS-SSS score, and FC level. MATERIAL AND METHOD: Patients with IBS-D and symptom exacerbation (n=100), active UC (n=25), and HC (n=30) were included. FC was measured in all groups. IBS…

Aliment Pharmacol Ther. 2026 Mar 13. doi: 10.1111/apt.70602. Online ahead of print. ABSTRACT BACKGROUND: Infection enteritis is associated with the development of irritable bowel syndrome (IBS) and functional dyspepsia. AIM: This study aimed to examine the long-term risk of IBS and functional dyspepsia, and associated health care utilisation following infection enteritis. METHODS: We conducted a retrospective cohort study using TriNetX U.S. Network. Adults with infection enteritis were identified and matched to controls, balancing demographics and comorbidities. Primary outcomes were the risk of incident IBS and functional dyspepsia diagnoses at 1, 5, and 10 years. Second…

J Clin Med. 2026 Feb 25;15(5):1727. doi: 10.3390/jcm15051727. ABSTRACT Background/Objectives: Irritable bowel syndrome (IBS) is a common and heterogeneous gastrointestinal disorder. Although numerous systematic reviews (SRs) have evaluated the effects of probiotics in IBS, uncertainty persists regarding their clinical effectiveness, methodological quality, and certainty of evidence. This umbrella review aimed to critically appraise SRs on probiotics in IBS, quantify overlap among reviews, and assess the certainty of evidence using the GRADE approach. Methods: We conducted an umbrella review of SRs of randomized controlled trials evaluating probiotics in adults with IBS. S…

Healthcare (Basel). 2026 Feb 24;14(5):562. doi: 10.3390/healthcare14050562. ABSTRACT Background: Psychological factors such as alexithymia, somatization, and their associated effects on health are consistently observed as key characteristics in the onset, maintenance, and chronic course of irritable bowel syndrome (IBS). This study aimed to investigate the presence and role of alexithymia, psychosomatic syndromes, and health status in individuals affected by IBS. Methods: The sample comprised 143 patients diagnosed with IBS, ranging in age from 18 to 78 years (M = 30.90, SD = 14.39), with a predominance of females (81.8%). The diagnostic protocol included a sociodemograph…

Nutrients. 2026 Feb 26;18(5):765. doi: 10.3390/nu18050765. ABSTRACT BACKGROUND/OBJECTIVES: Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder affecting approximately 5-10% of the population, with many individuals reporting insufficient improvement from treatment options. This study aimed to explore whether time-restricted eating (TRE) could alleviate symptoms in patients with IBS. METHODS: This single-group, pre-post pilot study included participants with IBS who followed an 8-week time-restricted eating protocol, defined as a daily 16 h fasting period and an 8 h eating window (16:8). Symptom changes were assessed using the validated IBS Symptom Seve…

Front Gastroenterol (Lausanne). 2022 Aug 12;1:959082. doi: 10.3389/fgstr.2022.959082. eCollection 2022. ABSTRACT Approximately 25% of people with quiescent inflammatory bowel disease (IBD) have symptoms caused by a functional gastrointestinal disorder (FGID). The pathophysiology of FGIDs in IBD is multifactorial. The gut-brain axis plays an important role as a bidirectional pathway with reciprocal gastrointestinal and psychological symptoms. Other factors include altered gastrointestinal motility, microbiome dysbiosis, medication use, prior surgery, impaired intestinal permeability, immune-system activation, and visceral hypersensitivity. As both IBD and certain FGIDs can…

Front Cardiovasc Med. 2026 Feb 25;13:1702012. doi: 10.3389/fcvm.2026.1702012. eCollection 2026. ABSTRACT INTRODUCTION: Irritable bowel syndrome (IBS) has been linked to poor health, high stress and diminished quality of life. Previous findings about associations between IBS and cardiovascular disease are, however, contradictory. Our objective was to examine 10-year cardiovascular risk, lifestyle factors, and self-rated health in people with IBS compared to a reference group. METHODS: Sweden's southernmost county (Scania) has implemented targeted health dialogues (THDs) in primary health care for all 40- and 50-year-olds. Before the THD, participants completed a questionna…

Acta Gastroenterol Latinoam. 2025 Dec 23;55(4):276-291. doi: 10.52787/agl.v55i4.570. eCollection 2025 Sep-Dec. ABSTRACT Small intestinal bacterial overgrowth was originally described as a cause of maldigestion and malabsorption, and its diagnosis was based on the culture of aspirates from the upper small intestine. The application of hydrogen breath tests to assess suspected small intestinal bacterial overgrowth increased the frequency of this diagnosis dramatically, and expanded its clinical context from maldigestion to include a number of non-specific gastrointestinal complaints and even some systemic ills. However, a critical review of recent literature suggests that r…

Front Gastroenterol (Lausanne). 2024 May 2;3:1342888. doi: 10.3389/fgstr.2024.1342888. eCollection 2024. ABSTRACT INTRODUCTION: Irritable Bowel Syndrome (IBS) is a highly prevalent functional gastrointestinal disease that is commonly associated with psychological comorbidities and maladaptive thought patterns. Previous studies report psychological therapies such as cognitive behavioral therapy (CBT) and gut-directed therapy (GDP) improve IBS symptom management and quality of life. This review seeks to understand the effectiveness of various psychotherapies across delivery methods for patients with irritable bowel syndrome. METHODS: A scoping literature review of PubMed ar…

J Gastroenterol Hepatol. 2026 Mar 12. doi: 10.1111/jgh.70322. Online ahead of print. ABSTRACT BACKGROUND: Recent years have seen greater interest, and hence, many trials published on the topic of probiotics as a treatment for irritable bowel syndrome (IBS). Given the anticipated "multiplicity problem" and inadequacy of traditional meta-analysis, this study aims to evaluate the efficacy of probiotics in alleviating symptoms of IBS and improve quality of life through a trial sequential analysis (TSA). METHODS: Medline, Embase, Web of Science, and Cochrane were screened for randomized controlled trials (RCTs) comparing probiotics to placebo in adult patients with IBS. Primar…

Neurogastroenterol Motil. 2026 Mar;38(3):e70272. doi: 10.1111/nmo.70272. ABSTRACT BACKGROUND: Irritable bowel syndrome (IBS) is a highly prevalent disorder of gut-brain interaction best understood within a biopsychosocial framework. Recent studies in other healthcare systems have suggested racial disparities in the management of IBS. AIMS: We aimed to investigate racial disparities in the diagnosis and management of IBS including adherence to national guidelines between White British and Ethnic minority patients with IBS in a UK secondary care setting. METHODS: Consecutive Ethnic minority patients (N = 68) with a coded secondary care diagnosis of IBS at a gastroenterology…

World J Methodol. 2026 Mar 20;16(1):107908. doi: 10.5662/wjm.v16.i1.107908. eCollection 2026 Mar 20. ABSTRACT BACKGROUND: Irritable bowel syndrome (IBS) is a common functional bowel disorder characterized by abdominal pain and altered bowel habits, with types classified based on stool patterns: (1) Diarrhea-predominant IBS (IBS-D); (2) IBS with constipation (IBS-C); and (3) Mixed IBS. This condition affects approximately 10% of adults globally and is challenging to treat due to the lack of definitive structural or biochemical markers. Treatment options include dietary, pharmacological, and psychological therapies, yet patients often struggle with refractory symptoms impac…

World J Methodol. 2026 Mar 20;16(1):107169. doi: 10.5662/wjm.v16.i1.107169. eCollection 2026 Mar 20. ABSTRACT BACKGROUND: Small intestinal bacterial overgrowth (SIBO) and irritable bowel syndrome (IBS) are common gastrointestinal disorders that significantly impact patients' quality of life and pose a financial burden on healthcare systems. SIBO is characterized by an abnormal increase in small intestinal bacteria, leading to symptoms such as malabsorption, diarrhea, bloating, and abdominal pain. IBS is a functional gastrointestinal disorder marked by recurrent abdominal pain with changes in bowel habits, and is subclassified into diarrhea-predominant IBS (IBS-D), constip…

Why Gastrointestinal Problems Often Affect Women Differently Yale Medicine Hormones, anatomy, and life stages can change how digestive symptoms show up for women—and when to seek care. Digestive issues are part of being human. But if you are a woman, they may show up more often, feel more intense, or follow a pattern—especially around your period, or during pregnancy or menopause. Spotting those patterns can help you know what’s normal and when to check in with a doctor. “Women tend to report more bloating, indigestion, and nausea than men,” says JoAnn Hong-Curtis, MD, a Yale Medicine gastroenterologist. “Hormonal changes across a woman’s life—and differences in anatomy…

Tenapanor is associated with earlier and sustained symptom relief in IBS-C - Therapeutic Advances in Gastroenterology In patients with irritable bowel syndrome with constipation (IBS-C), rapid, sustained relief from constipation and abdominal symptoms, such as pain, discomfort, and bloating, can improve quality of life. WALTHAM, Mass., March 09, 2026 (GLOBE NEWSWIRE) -- Ardelyx, Inc. (Nasdaq: ARDX), a biopharmaceutical company focused on the development and commercialization of innovative medicines that meet significant unmet medical needs, today announced the publication of data from its IBS-C clinical development program, “Tenapanor is associated with earlier and susta…

Common Grain Compound May Help Control Irritable Bowel Symptoms SciTechDaily A naturally occurring compound in rice bran may play an unexpected role in regulating intestinal movement. A team of scientists led by Dr. Keisuke Obara, Dr. Kento Yoshioka, and Professor Yoshio Tanaka from the Faculty of Pharmaceutical Sciences at Toho University has discovered that ferulic acid(FA), a naturally occurring polyphenol found in high amounts in rice bran, can reduce contractions in intestinal smooth muscle. The compound appears to work by blocking voltage-dependent calcium channels, which play a key role in muscle contraction. View the full article

Med Clin (Barc). 2026 Mar 4;166(5):107388. doi: 10.1016/j.medcli.2026.107388. Online ahead of print. ABSTRACT BACKGROUND: Dietary habits are closely related to symptom modulation in irritable bowel syndrome (IBS), yet their characterization remains limited. Understanding habitual food intake in IBS patients may contribute to diagnosis and support personalized management. OBJECTIVES: To identify dietary patterns associated with IBS and to develop a diet-based score to aid in clinical stratification and nutritional guidance. METHODS: A case-control study was conducted including 109 participants (53 IBS patients and 56 healthy controls). Dietary intake was assessed using a v…