IBS Medications, Medical Foods and Fecal Microbiota Transplantation (FMT)

I’ve been taking Zoloft for depression for many years. Has anyone tried Cymbalta for both depression AND IBS? Either standing alone or with other meds?

I am having a terrible, long flare-up of IBS-D. I am considering trying the antibiotic, Rifaximin. Has anyone had experience with this drug? beneficial?

I hope this community can shed some light on a topic I've been delving into lately. I've been dealing with Irritable Bowel Syndrome (IBS) and have come across information about the potential benefits of Human Milk Oligosaccharides (HMOs) in managing digestive issues. I'm curious to know if anyone here has tried incorporating HMOs into their IBS management plan and if you've noticed any positive effects. If you've found success with HMOs, I'd love to know which products or sources you recommend. On the flip side, if you've encountered challenges or haven't noticed any improvement, I'm still keen to hear your perspective. Additionally, any tips on dosage, duration, or facto…

Greats news for Canadians 🇨🇦 about access to VIBERZI for IBS-D. Abbvie Canada has reversed the decision to discontinue VIBERZI (eluxadoline 75mg & 100mg tablets). To help mitigate the current shortage, Health Canada has allowed importation and distribution of US-labelled VIBERZI.

Has anyone tried ADHD medications to improve IBS-D? Before I started imodium and lomotil, a doctor had me try Strattera. It made my IBS a little better, but I didn't like the other side effects. What about all the other ADHD medications? Do they improve IBS or make it worse?

Ardelyx Showcased Encouraging Data on Treatment Satisfaction and Efficacy of IBSRELA® (tenapanor) for IBS-C GlobeNewswire WALTHAM, Mass., Sept. 11, 2023 (GLOBE NEWSWIRE) -- Ardelyx, Inc. (Nasdaq: ARDX), a biopharmaceutical company founded with a mission to discover, develop and commercialize innovative, first-in-class medicines that meet significant unmet medical needs, shared encouraging data on IBSRELA® (tenapanor) via two poster presentations presented at the 2023 Gastroenterology & Hepatology Advanced Practice Providers (GHAPP) Annual Conference currently being held in National Harbor, Maryland September 7-9. IBSRELA, discovered and developed by Ardel…

Hi I’m new here. I just started Linzess this morning for my IBS-C/sluggish colon. It’s been years and now for the last 8 months I can only go with a gloved hand and removing the hard dry balls of bowel myself. I’ve been taking magnesium every day, but it stopped working. I finally gave in and tried psyllium husk and miralax yet again.....but nothing. I’ve stopped all carbonated drinks and stopped taking most of my medications. I also have a perineal prolapse. I’ve tried not to take too many laxatives in the past as to not be dependent, but at least they would work when I did use them. I don’t know why they don’t work anymore. I can’t really “push” anymore…

I read the following study Targeting Histamine Receptors in Irritable Bowel Syndrome: A Critical Appraisal (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503283/) as I already had Zyrtec (citrizine) in my home I decided to try it. I have relief for the first time in years from bloating, distension and nausea. I am also following an antihistamine diet that was given to me as a child. That means not only the food, but how it is prepared and kept. The antihistamine diet does not have anything to do with being allergic to food nor is the antihistamine being used for food allergy. It is about the mast cells that release histamine whether in the skin, lung or …

Dose Linzess cause you to retain water

My history: web.archive.org/web/20220801072636/https://old.reddit.com/r/HumanMicrobiome/comments/8sv31e/my_detailed_experiences_lessons_from_8_different/ www.youtube.com/watch?v=6wi52tLjCps I've been following the microbiome research, doing FMTs, and trying to find a highly effective donor for the past decade. I created HumanMicrobiome.info (see IBS section) to try to help other people get up to date on what I feel is the obvious crux of the issue. I tried to go through official channels for years to push for FMT clinical trials with high quality donors, but when that failed I took things into my own hands and started up HumanMicrobes.org. I st…

Has anyone done FMT for IBS-D? Which clinic? And how long did the effectiveness of FMT lasted? Thank you

Fecal Microbiota Transplantation (FMT) is a new treatment where healthy stool donor is transplanted into the colon of the patient. Detailed explanation: Fecal Matter Transplantation (FMT) is a procedure where a fecal solution from a donor is deposited into the intestinal tract of a recipient. To complete the procedure, the fresh or frozen stool of the donor, is dissolved in a salt water solution. The fecal matter is usually deposited using a tube that goes straight into the digestive tract. The treatment is generally recognized as safe. Most patients experience diarrhea on the day of the procedure, and a small percentage report belching, abdominal cramping or co…

I would love to know if there is any hope of Viberzi coming back to Canada soon. I was devastated a few weeks back to hear it was canceled. I have been taken it for over a year and it really help with you IBS-D

I have IBS-C. I usually don't go for 5 days. Then, the cramps come and eventually after several hours, I will finally start to move my bowels. But, having been so constipated for days, I always end up with 2 days of diarrhea, going maybe 4 to 5 times in the day with small amounts. Then the cycle of constipation resumes. When should I start the medication? Should I wait till the diarrhea stops?

So I started Ibsrela this week. I don't hate it, but....I can't seem to get the dosage right. My doctor wanted me to take 1/2 pill in the morning with salt in the meal and it didn't work at all. 3/4 of a pill does not work. One pill works a little too well. Total liquid. It actually doesn't bother me except that it kicks in again in the afternoon after lunch or just happens. I don't see this as a long term option for when I need to be somewhere at a certain time. If anyone has taken Ibsrela and can get it to work normally, please share, such as the timing, amount of sodium, etc. I am actually glad to be trying this. I wish I had a sample pack of all the constipa…

For years, I was treated as if I have D-predominant IBS, never finding any relief because everything I was instructed to do made things worse, it would seem. On a whim, last year, I started treating myself as if I am C-predominant. I always sort of suspected, because the diarrhea only seemed to follow a long pause (days) between stools and usually was real hard stool followed by full blown liquid. My issue was described as a hyperactive gastrocolic reflex causing the urgent runs to the RR after eating. I can agree that is the case because if I eat slightly more than it can handle, I get a nasty reaction. I definitely don't agree with D-predominant IBS. I have b…

Is there a Linzess savings program for folks with Medicare

Scoop: AbbVie drops IBS drug Viberzi in Canada, 'devastating' patients Endpoints News AbbVie has since confirmed to Endpoints that it is discontinuing Viberzi in Canada this year “as a result of our regular business prioritization review.” The drug will continue to be available in the US, as well as the UK — where Sam lives — with “no plans to discontinue,” a spokesperson said. It had already been discontinued in the EU back in 2020 at the request of Allergan, the drug’s initial manufacturer before the $63 billion AbbVie buyout that year. The pharma company declined to offer further explanation of its reasoning behind the discontinuation, adding that there “ar…

We recently achieved complete and deep remission by modulating the microbiome using specific synbiotic formulation (Prebiotic + Probiotics+ Antioxidants) a supplement, for a 12 year old Crohns patient. With in 4 weeks Calprotectin levels dropped by 60% and by end of 12 weeks all biomarkers were normal. The colonscopy images before and after are available and I do not know how to attach here. Histology of the biopsy samples showed no inflammation and deep remission that was confirmed by gastroenterologist at Children's Hospital of Philadelphia. We were able to get maintain and continue the patients on solid foods with no other medications. Would love to add more details an…

I’ve struggled with IBS-D since childhood (I’m mid-30s now). I had a colonoscopy and many tests run years ago and everything came back normal so they just told me I had IBS and sent me along. My IBS is worst in the morning and I struggled to maintain employment. Eventually I resorted to taking 4 Imodium when I woke up and more as needed throughout the morning. I decided to go see the doctor again and they are planning to do another colonoscopy. I had many stool tests and of course everything is normal. The only abnormal test I’ve ever gotta back is that my IgA is quite elevated, but my doctor seems unsure of what that means. Anyway, she ended up prescribing me lomotil and…

While at DDW I visited with the pharmaceutical that makes IBgard®. IBgard® uses patented technology to allow peppermint to be absorbed in the small intestine instead of the stomach. Peppermint is known to be a smooth muscle relaxer. It has been used for digestive illness for many years. Peppermint oil is widely recommended by doctors for soothing the bowel related to abdominal pain. I decided to try it for myself. The capsules are green and are easy to swallow. Within 5 minutes I felt a sensation of bursting peppermint in my stomach. It was actually kind of uncomfortable. The instructions indicate that this is not unusual. Within 30 minutes the feeling dissipate…

my Dr told me to eat high fiber food for a month. instead i ate cheese puffs and drank coffee, it really cleared out my blocked bowels. much love Lauren the IBS QUEEN.

Good morning, I was told to take Creon by my gastroenterologist for fat malabsorption. She told me I had a mild form of Pancreatitis. However when I take it, I don't notice any significant benefit. It is extremely expensive, though my plan currently covers it. Still if it doesn't seem to work so I can't see the point in taking it. Has anyone found any digestive enzymes or other medications to help with digesting fat? thanks in advance for your ideas.

LAVAL, QC, Feb. 8, 2022 /CNW Telbec/ - Bausch Health, Canada, part of Bausch Health Companies Inc. (NYSE: BHC) (TSX: BHC), ("Bausch Health" or the "Company") today announced the availability through pharmacies across Canada of its new prescription treatment TRULANCE® (plecanatide). TRULANCE is approved by Health Canada for the treatment of irritable bowel syndrome with constipation (IBS-C) in adults, and is the first treatment brought to market in Canada by the gastrointestinal division of the Company. Canadian treatment guidelines for IBS-C recommend a variety of non-pharmaceutical and pharmaceutical approaches to treatment, but 70 per cent of surveyed IBS-C patient…

Read about this steroid and wondered if might be helpful. Topical budesonide improves collagenous gastritis symptoms: Study (medicaldialogues.in)