IBS Medications, Medical Foods and Fecal Microbiota Transplantation (FMT)

Jeffrey Roberts, what do you tell me about Dr. Mark Pimentel's research? which line of research do you find closest to unlocking the secrets of IBS? My symptoms seem to be an allergic reaction. Sometimes I believe there might be some bacteria behind it causing it all.

I take Linzess to help manage by IBS symptoms, the strongest dose. I take one pill a day, as recommended. I was wondering if anyone has taken more than one a day, if this is at all possible, because I feel that while it is helping it might be more effective in cleaning me out if I had a little more. Advice?

So my doctor prescribed me Amitiza today and I was wondering what others peoples experiences were with it? I have previously tried Linzess twice and it worked, but too well, and each time I ended up severely dehydrated and nauseous while constantly running for the restroom. I'm hoping Amitza will relieve my IBS-C without any bad side effects because Linzess was nothing I could take and go to work for sure.

I have had constipation off and on my whole life - was diagnosed with IBS a few years ago, and recently went to a GI doctor. Linzess did not help, either diarrhea or constipation using it. I am on my 4th day of taking Motegrity, worked great the first day, okay the second, and I am back to straining, with lots of abdominal gas. I am starting pelvic floor exercises today, which I hope helps. Anyone have these experiences with Linzess or Motegrity? pp

After months of taking Linzess, I continue to have diarrhea, every day. Would a lower dosage help? Or best foods to eat after taking it? Any help would be appreciated.

Mainly I'm asking because I am trying colloidal silver for a mild infection right now. Since trying it (5 days ago) I have had slightly loose bm's again. Stuck between a rock and a hard place. If I don't try it, I will be forced to take antibiotics, which I sense will devastate my gut, as they once messed me up when I was normal. The usual instructions -to simply take probiotics! ....are not going to work for me. I can tolerate neither nowadays. I had never trie colloidal silver before. Has anyone here any experience of using it? I am not talking about the stuff that turns you blue with argyria (proteins and stuff in it) but pure high quality nano particle colloidals…

Hi, I have a remission in my IBS-C symptoms after 10 years. I have extreme abdominal pain and cramping right before going to the bathroom and while there and after that. I have about 3 episodes of extreme pain and I screamed so much during one of the episodes that I lost my voice. I went to ER twice in the last 48 hours and they just gave me hydrocodone. The hydrocodone is not helping with the pain at all. I was wondering if anybody has similar IBS symptoms and what they did to manage the pain. Or maybe this is not IBS and it's something else. I did a colonoscopy 10 years ago and they did not find anything.

Hello again I was recently given some kefir grains, recommended by a (non-expert) friend 'to help with your gut symptoms'. A brief bit of online research suggested that efficacy is, indeed, supported by medical research, so I was willing to try. A fortnight in and I'm experiencing regular, fairly intense nausea and minor headaches. Reading around again, I note that this is a common response (and one that I somehow didn't pick up on initially when reading) but advice seems to differ on whether to 'plough through and it'll improve' or reduce/stop consumption. I've also recently ended a short course of Rifaxamin (which almost completely cleared my abdominal pain an…

I was recently placed on Nortriptyline 25 mg once daily before bed. I've been taking it since October 26. I'm an avid runner with a resting heart rate in the low 60s to mid 60s. The past week my heart rate has been increasing. I'm now 82 but when sitting my heart rate has trouble getting out of the low 100s. I've been light headed and I checked my blood pressure twice since yesterday and it's been borderline low. I got flagged a few times BEFORE the new medication for low blood pressure. I see both of these are potential symptoms of the med. I can't speak with my doctor until Monday, but I'm going to drop my dose to every other day starting today. This isn't a side effec…

Hi all, I'm a woman in my mid-twenties, and have been suffering from IBS-D for the past ~10 years. I believe I began having gastro issues after my appendix was removed, post burst. I have had a colonoscopy, have gone through many rounds of testing and fecal sampling, etc --- and always get the "I guess its just IBS" diagnosis. After I go through a round of investigative testing, I am usually exhausted, and done with a flare up, so I stop my hunt. I am now determined to take charge of my health, as it seems my flare ups are getting progressively worse, and are certainly linked to anxiety. I take a probiotic (ProbioMax + DF) and an SBI Protect powder once …

My doctor as recently told me that perhaps probiotics could help me. I know pretty much nothing about probiotics. He prescribed me some but I wanted to see if anyone has tried different probiotics with different results. I’m going to be taking the ones he gave me but if there’s a chance that a different one might help I don’t want to rule out probiotics entirely. Are they pretty much all the same? Should I try different types or if one type doesn’t work out for me can I pretty much rule them all out?

I do intermittent fasting. First meal at noon and last 7-8 pm. I work out in the morning. How would it be if I took I took it at bed time, so I'll go to the bathroom before workout??? I've had chronic C my whole life, can be very frustrating!!!! Look forward to getting an answer!! Thank you, Lori T.

Hello All, I have never thought of looking for a support group until about 1 hour ago. I have been experiencing left side pain and raw feeling in the bowels for several years now. Taking a cocktail of vitamins and mineral has dropped the symptoms by 95 percent. There is still one symptom that haunts me and is getting worse. Im not sure where to begin to determine if its food related or something more. Below my tailbone i feel rawness and severe inflammation that encompasses the buttocks as well. My doctors say its all in my mind but i think we all know how absurd that diagnosis is. I'm wondering is the foods i am eating are causing inflammation in my stool that feels…

Hi, I have started suffering with IBS-d for about two years. I was just prescribed Viberzi, which works and makes me feel normal. But my insurance only pays 33% .

New research: Faecal transplantation helped many with IBS A new Norwegian study reports that many patients treated with faecal transplantation felt completely healthy after treatment. Everyone in the study was given bacteria from a single donor with a special gut flora. https://sciencenorway.no/bacteria-intestines-irritable-bowel-syndrome/faecal-transplantation-helped-many-with-ibs/1606610 PubMED Publication: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628324/ BMJ: https://gut.bmj.com/content/early/2019/12/18/gutjnl-2019-319630

Pharmacologic recommendations for IBS medication are different depending on the medical association. American College of Gastroenterology (ACG) Americal Gastroenterological Association (AGA) Canadian Association of Gastroenterology (CAG)

Hey Guys, I have IBS C/D from many years. Last week, I did FMT with help of a friend at home ( 8 sessions). Its been 3 days and I dont see any changes in my IBS. How long does it take to see any positive results. Regards

Important Safety Alert Regarding Use of Fecal Microbiota for Transplantation and Risk of Serious Adverse Reactions Due to Transmission of Multi-Drug Resistant Organisms The FDA published a bulletin last week about FMT. FMT isn't something that is advocated for IBS at this time; however, this bulletin is worth sharing to highlight the risks of trying FMT. https://www.fda.gov/vaccines-blood-biologics/safety-availability-biologics/important-safety-alert-regarding-use-fecal-microbiota-transplantation-and-risk-serious-adverse

Hey there! My Doctor 2 years ago (first one to ever take my IBS symptoms seriously - another point for the importance of female doctors) prescribed me Olestyr (brand name for Cholestyramine) for my *ahem* (explosive) Diarrhea symptoms. This symptom is definitely the most disruptive and unpredictable of all of my symptoms, and while my IBS continues to challenge me, having this medication has been my saving grace, and made me feel like I have a chance at a normal life again. It's not the easiest medication to manage day-to-day as it's a powder and requires being mixed in with water. So at dinners or social gatherings I've taken to bringing an opaque thermos and pre-mi…

Has anyone tried it? I’m taking Mega sporebiotic and I thought it was helping but not really. Anyone else tried it? This IBS Clear looks interesting. Gastro guy is no help at all. Just says take Linzess (I have IBS-M so that’s not helpful) and IBGuard which is meh and come back in 4 months!!! No help at all.

For anyone in Canada (or UK) that was using Buscopan for abdominal pain, it has been on backorder for almost 1 year due to the factory being damaged by an earthquake. The product was expected to be available again mid-January 2019, however, now it has been pushed back again until at least March 2019, but maybe even until June 2019. https://www.buscopan.ca Thanks to Michael Mahoney who also has told me that Buscopan tablets may be available in the UK. The UK had a backorder of the injectable form, but apparently has the tablets. They can be ordered on Amazon. You might consider Donnatal (available in the US, but very expensive) if you found relief from Buscopan. …

B"H, From age 26 until now at age 66 IBS was horrible, the worst being also gas and my many year job had only a children's toilet at the small school I taught for decades. I would have used it probably 5 times an hour, but then I'd have any of the 30 kids banging on the door, and I would not be able to teach! The last few years it got so I could not even leave the house, and started on adult diapers. Than G-d last week I bought "Activated Charcoal" capsules, a vegetable charcoal (and Kosher)!It IS WORKING! I had 40 years of all the IBS symptoms with horrible gas pains. The gas propelled a bit of......out uncontrollably , worse made hemorrhoids. The "Activated Charcoal"…

Well I just received my package from Russia containing Iberogast manufactured by Bayer. I am glad it made it thru customs. I am hoping this will help since some of the ingredients work on the 5-ht4 agonist which is what zelnorm worked on. Zelnorm was the only thing that has ever worked for me but they pulled it from the market.

Jury finds probiotic seller of VSL#3 a probiotic sold for IBD & IBS liable for false advertising & awards product inventor. True proprietary formulation is only available in Visbiome. VSL#3's current knock-off formulation has never been tested. Stop using it! https://apnews.com/e75b0af23b294344913ac4ff65bf2fa1

Anyone using Trulance (plecanatide) for IBS-C or CIC? The manufacture Synergy just filed for bankruptcy protection and is going to be bought by Bausch Health, formerly Valeant. Hopefully business as usual. https://ir.synergypharma.com/press-releases/detail/1882/synergy-pharmaceuticals-announces-agreement-for-bausch