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My GI doctor suggested I take tiny doses of something like Prozac to help with my "sensitive stomach" since everything I eat hurts me and I've ruled out all other possible causes. This seems like my only answer for now although I'm not crazy about the idea, even if it is a tiny dose. Does anyone have experience with this?

If you would like to see a complete list of medications used as treatments for IBS, please visit our Types of Medications page on our website, https://www.ibspatient.org/medications/

L Chang: Wide prevalence of comorbid conditions in IBS. Quality of Life (QOL) suffers with the greater number of conditions L Chang: FGiDs (Functional Gastrointestinal Disorders) and IBS comorbidities especially significant for women L Chang: Role for central neuromodulators (antidepressants) for managing FGiDs and IBS L Chang: Tricyclic antidepressants are considered first line for pain modulation. SSRI's antidepressants not as effective for GI pain. SNRI's antidepressants effective for pain. Tetracyclic antidepressants for early satiety, nausea/vomiting, weight loss and sleep disturbance L Chang: New data with pregabalin (Lyrica) for greater than 3 FGiD pain attacks per month. Could be considered for pain L Chang: Co-morbid migraine: CGRP receptor antagonist for IBS-D/M might be an option