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I have just been prescribed Linzess for my chronic C, it is so bad right now I can't eat without pain, seriously impacted throughout my colon. I do not want to take it during the day due to my work schedule. I am thinking I could take it when I get off work at 4pm since we don't eat till the earliest 5 but sometimes as late as 7. My stomach should be empty since I won't eat since lunch. I don't go to bed till around 10pm so should have plenty of time to clean out. Thoughts on whether this would be ok to do or not?

Hi All, I'm new to this group, having just left another one that scared the hell out of me. I do have mental health issues, which I'm sure contribute to my daily struggles with IBS-C, and I do have a story, but will let you know for now I suffer from debilitating anxiety, equally debilitating IBS-C, have very little medical support, am on Constella (or Linzess, as it's know in the US), don't use stimulate laxatives, and am wondering what your views of long-term use of Constella happen to be? It's not classified as a laxative, and has no stimulant properties, and I've been on it for two years as max dose. Can anyone provide their own experiences with Constella, along with their idea about its safety for long-term use, and perhaps offer any suggestions about how I may manage IBS-C, which I've had for years and has destroyed my life (along with many other things -- I'll provide a bio later, but since the other group was not very supportive and kept telling me Constella/Linzess is a laxative, will fail, and I'd better be prepared to suffer ever more unless I did this, this, and that, I'm tentative about share too much. I will tell you' I'm 43, posted this in the IBS-C forum but didn't realize there was an introduction process, and I apologize. I am a supportive person, very sensitive, and incredibly empathetic. Any replies that are kind and not combative or dismissive would be incredible. Thank you, Seroquelled

Hi All, I'm new to this group, having just left another one that scared the hell out of me. I do have mental health issues, which I'm sure contribute to my daily struggles with IBS-C, and I do have a story, but will let you know for now I suffer from debilitating anxiety, equally debilitating IBS-C, have very little medical support, am on Constella (or Linzess, as it's know in the US), don't use stimulate laxatives, and am wondering what your views of long-term use of Constella happen to be? It's not classified as a laxative, and has no stimulant properties, and I've been on it for two years as max dose. Can anyone provide their own experiences with Constella, along with their idea about its safety for long-term use, and perhaps offer any suggestions about how I may manage IBS-C, which I've had for years and has destroyed my life (along with many other things -- I'll provide a bio later, but since the other group was not very supportive and kept telling me Constella/Linzess is a laxative, will fail, and I'd better be prepared to suffer ever more unless I did this, this, and that, I'm tentative about share too much. I am a supportive person, very sensitive, and incredibly empathetic. Any replies that are kind and not combative or dismissive would be incredible. Thank you, Seroquelled