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My history: web.archive.org/web/20220801072636/https://old.reddit.com/r/HumanMicrobiome/comments/8sv31e/my_detailed_experiences_lessons_from_8_different/ www.youtube.com/watch?v=6wi52tLjCps I've been following the microbiome research, doing FMTs, and trying to find a highly effective donor for the past decade. I created HumanMicrobiome.info (see IBS section) to try to help other people get up to date on what I feel is the obvious crux of the issue. I tried to go through official channels for years to push for FMT clinical trials with high quality donors, but when that failed I took things into my own hands and started up HumanMicrobes.org. I struggled for a while, then a video went viral on social media resulting in tens of thousands of stool donor applicants. After ~23,000 we tried the #1 ranked donor. Results were mediocre but many people improved. A while later we activated another donor, but still results haven't been spectacular. Last year I raised prices & donor-payouts significantly. That seemed to be the necessary catalyst, and resulted in lots of viral videos and 500k+ stool donor applicants. I've been surprised at how rare my ideal stool donor criteria are. I still haven't found an ideal donor, but I'm still working through all the applicants. I would welcome collaboration from other research groups to assess our donors to try to figure out how to identify highly effective donors (IE: super-donors). Otherwise, it's up to us patients to continue to experiment and try to figure things out on our own. Also, I'm spending a ton of time screening "average" people. My efforts to recruit the types of people I think are most likely to qualify - top athletes - haven't been very successful. So I would welcome assistance in that regard.

Hey Guys, I have IBS C/D from many years. Last week, I did FMT with help of a friend at home ( 8 sessions). Its been 3 days and I dont see any changes in my IBS. How long does it take to see any positive results. Regards

Research study: A Pilot Study to Evaluate Fecal Microbiota Transplantation in Irritable Bowel Syndrome Location: Boston, Massachusetts Inclusion Criteria: IBS with diarrhea The study is to evaluate whether we can change the microbiome of individuals with IBS using a healthy donor. We then would like to see whether if we are able to change the microbiome, if there's a resulting improvement in symptoms. We randomize people to receive either a fecal transplant or a placebo fecal transplant. People are also receiving an antibiotic either rifaximin, a combination of Cipro/flagyl or no antibiotic as a pre-treatment. The capsule form of fecal matter transplant (FMT) is being used. Contact: Vivian Cheng 617.667.0682 vcheng2@bidmc.harvard.edu Principal Investigator: Anthony Lembo, MD, Beth Israel Deaconess Medical Center More clinical trials listed here: https://www.ibspatient.org/clinical-trials