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Many people diagnosed with IBS-D may actually have Bile Acid Malabsorption (BAM). I found this article from the Mayo Clinic (link below) and asked my doctor if i could try Colesevelam, and it has worked for me. 32 days with no diarrhea, not once! Dosage is between 2 - 6 tablets per day. i started at 6 and it's a little constipating so i've been decreasing and am now at 3 per day. My insurance covers it, and no other side effects. i can't tell you what a difference this has made in my life! https://www.mayoclinic.org/medical-professionals/digestive-diseases/news/identifying-diarrhea-caused-by-bile-acid-malabsorption/mac-20430098