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How is PEG-3350 ('Miralax') working for you?

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Hi. 62 y.o. male, MPH student, Post-infectious IBS-C. I've always been prone to constipation, but after post infection shigella a year and a half ago, I got pretty severe, chronic diarrhea, became malnourished, and ended up on a capful of PEG-3350 ('Miralax' I prefer generic names to avoid confusion) daily. Overall, it's been a lifesaver but it has had some serious drawbacks too (bloating, gas, queasiness, loss of strength). Last night I went down to 3/4 of a cap with no ill effects or constipation. I'm going to try 3/4 dose again tonight and see what happens.

Glad to be here and looking forward to exchanging stories and med. info.

  • 3 weeks later...
On 6/10/2026 at 7:19 PM, Philip Mark said:

Hi. 62 y.o. male, MPH student, Post-infectious IBS-C. I've always been prone to constipation, but after post infection shigella a year and a half ago, I got pretty severe, chronic diarrhea, became malnourished, and ended up on a capful of PEG-3350 ('Miralax' I prefer generic names to avoid confusion) daily. Overall, it's been a lifesaver but it has had some serious drawbacks too (bloating, gas, queasiness, loss of strength). Last night I went down to 3/4 of a cap with no ill effects or constipation. I'm going to try 3/4 dose again tonight and see what happens.

Glad to be here and looking forward to exchanging stories and med. info.

You might want to try eating cabbage seasoned with only oil and tomato. It helps hugely against constipation.

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