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Pubmed-Medical Therapies for Diarrhea-Predominant Irritable Bowel Syndrome


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Gastroenterol Clin North Am. 2021 Sep;50(3):611-637. doi: 10.1016/j.gtc.2021.04.003.

ABSTRACT

Diarrhea-predominant irritable bowel syndrome is a common functional gastrointestinal disorder that manifests with abdominal pain and diarrheal bowel patterns, without structural explanation. Diarrhea-predominant irritable bowel syndrome is a heterogeneous condition resulting from diverse pathophysiologic processes. Treatment strategies with varied mechanisms of action are beneficial in its management. The clinician must become familiar with a multi-dimensional approach to irritable bowel syndrome. The 3 approved medications are central to disease management. Effective treatment uses off-label medications and emerging therapies and a growing number of over-the-counter and supplemental agents to optimize symptom improvement for the patient with diarrhea-predominant irritable bowel syndrome.

PMID:34304791 | DOI:10.1016/j.gtc.2021.04.003

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