Jump to content

Take 2: Started Viberzi (eluxadoline) again... will keep a new log here


Jeffrey Roberts
 Share

Recommended Posts

Jeffrey Roberts

image.png

I met with my GI doctor a couple of weeks ago after a colonoscopy to rule out anything other than IBS. The scope was normal. The doctor suggested Viberzi for my IBS-D which sometimes morphs into IBS-M. I'd say overall I was IBS-M so while Viberzi isn't exactly for my situation I asked to give it a try again.

From my last experience with Viberzi taking 100mg twice daily interacted with my cholesterol meds and made me very constipated so I had to stop.

This time I was given a dose of 75mg twice daily. I had a feeling that because my IBS-D morphs into IBS-M that I still might have a problem with constipation.

This is how the first 10 days went:

Day 1: 75 mg at mid-day with food.

Similar spaced out feeling initially, but that went away after 1-2 hours. Some cramping. No BM.

Day 2: Early morning BM, but no cramping. Took 75 mg at mid-day with food.

Spaced out again. This seems to be the new normal.

Day 3: No BM. Took 75 mg at mid-day with food.

Day 4: No BM. I didn't take the Viberzi because I was concerned I might be getting constipated.

Day 5: No BM. Oh oh... I'm constipated. No Viberzi.

Day 6: No BM in the morning. Starting to thinking about using some miralax as a rescue drug to get things moving. Instead, I drank heaps of caffeinated tea to get things moving. Tiny little BM resulted.

Day 7: 3 very large BM's fully formed. Took 75 mg after lunch.

Day 8: 1 normal BM. No pain.

Day 9: 1 normal BM. No pain.

Day 10: No morning BM. Took 75 mg with breakfast although I thought I was going to have a BM after breakfast, but I didn't. Had 1 BM later in the afternoon.

The first 10 days told me that Viberzi is extremely potent for me. I'm going to stick to a gap of 2 days between tablets and see if I have BM's in between the days that I'm not taking it.

My impression is that it's gentler than Imodium, le: no cramping, although like Imodium it really stops me up.

Stay tuned...


Link to post
Share on other sites

Jeffrey Roberts

Day 11: Was out for dinner in a restaurant last night and it didn't sit well. Had a very uncomfortable sleep and had 3 BM's this morning. All formed, not painful. Was tempted to take 75 mg of Viberzi, but holding off for every 3rd day so that I don't get into a cycle of D - C - D - etc...

Link to post
Share on other sites

Jeffrey Roberts

Day 12: 1 BM formed, not painful.

Day 13: Took 75mg Viberzi. 1 BM in late afternoon.

Day 14: No BM and have the feeling that I'm constipated.

Link to post
Share on other sites

Jeffrey Roberts

Day 15: 1 BM before breakfast. Stool didn't look like constipation. 3 more large BM's in the morning with a fair amount of cramping. I took 75mg Viberzi mid-morning. Perhaps I need to take this every other day as I seem to be running into problems waiting for the 3rd day.

Link to post
Share on other sites

Jeffrey Roberts

Day 16: 1 small BM after breakfast.

Day 17: Cramping after breakfast and 1 solid BM. Took 75mg Viberzi after breakfast.

Link to post
Share on other sites

Jeffrey Roberts

I didn't take 75 mg Viberzi again until Day 22. I had 1 BM everyday up until Day 22 when I had 3 BM's.

Clearly I am not using Viberzi how it was intended to be used; however, for me it is allowing me to get by without days bogged down by 4-5 BMs and pain.

Going to continue this regiment of taking it almost as needed and will report back.

Side effects to date are a spaced out feeling within 1 hour of taking the medication and a noisy stomach that sounds like liquid being squeezed through a small opening. Don't know how else to describe that. :)

Link to post
Share on other sites

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

 Share

×
×
  • Create New...