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Pubmed-Future of Brain-Gut Behavior Therapies: Mediators and Moderators

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Gastroenterol Clin North Am. 2022 Dec;51(4):723-739. doi: 10.1016/j.gtc.2022.06.011. Epub 2022 Oct 20.


With growing evidence to support their efficacy, brain-gut behavior therapies are increasingly viewed as a key component to integrated care management of disorders of gut-brain interaction. However, the types of brain-gut behavior therapies differ in how and for whom they purportedly work. We provide a conceptual review of these brain-gut behavior therapies, with an emphasis on describing how (ie, mechanisms) and for whom (ie, moderators) they work as hypothesized and/or supported by evidence. Based on evidence to date, we recommend that brain-gut behavior therapies prioritize gastrointestinal-specific targets, such as gastrointestinal-specific anxiety.

PMID:36375992 | DOI:10.1016/j.gtc.2022.06.011

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