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Pubmed-Letter: Irritable bowel syndrome and antibiotics

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Aliment Pharmacol Ther. 2024 Feb;59(3):421. doi: 10.1111/apt.17837.


This article is linked to Staller et al papers. To view these articles, visit https://doi.org/10.1111/apt.17736 and https://doi.org/10.1111/apt.17839


As Staller et al. reported, increased antibiotic dispensing to patients up to 1 year before the diagnosis of irritable bowel syndrome (IBS) could imply alteration of the gut microbiota in the pathogenesis of IBS.1 However, increased healthcare costs include more treatment with many systemic antibiotics after IBS is diagnosed compared with subjects without IBS.2 Since many patients have symptoms for years before they are attributed to IBS, it seems possible that undiagnosed IBS contributed to the findings of Staller et al.

PMID:38197706 | DOI:10.1111/apt.17837

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