A Pilot Study to Evaluate Fecal Microbiota Transplantation Engraftment in Irritable Bowel Syndrome

  • Posted on: 15 January 2018
  • By: researcher

The study is to evaluate whether we can change the microbiome of individuals with IBS using a healthy donor.  We then would like to see whether if we are able to change the microbiome, if there's a resulting improvement in symptoms.  We randomize people to receive either a fecal transplant or a placebo fecal transplant.  People are also receiving and antibiotic either rifaximin, a combination of Cipro/flagyl or no antibiotic as a pre-treatment.  The capsule form of fecal matter transplant (FMT) is being used.

Boston, Massachusetts
Both Female and Male
18 to 80 years
Study Duration: 
10 weeks
Inclusion Criteria: 

IBS with diarrhea

Thursday, July 28, 2016 to Thursday, May 31, 2018

Vivian Cheng

Principal Investigator: Anthony Lembo, MD, Beth Israel Deaconess Medical Center