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Twitter-RT @DRADFARMER1: Higher prevalence of joint hypermobility in constipation predominant irritable bowel syndrome - Zweig - 2018 - Neurogastro…

Oct 24, 2018
RT @DRADFARMER1: Higher prevalence of joint hypermobility in constipation predominant irritable bowel syndrome - Zweig - 2018 - Neurogastro… (RSS generated with FetchRss) View the full article

Google-How Stress Impacts Your Number 2s

Oct 23, 2018
How Stress Impacts Your Number 2s Care2.com Full coverage View the full article

Google-Serum-derived bovine immunoglobulin for children with diarrhea-predominant irritable bowel syndrome

Oct 23, 2018
Serum-derived bovine immunoglobulin for children with diarrhea-predominant irritable bowel syndrome Dove Medical Press Full coverage View the full article

Google-When Your Child Literally Can't Poop

Oct 23, 2018
When Your Child Literally Can't Poop Scary Mommy Full coverage View the full article

Pubmed-Gastroparesis in Non-Diabetics: Associated Conditions and Possible Risk Factors.

Oct 23, 2018
Related Articles Gastroparesis in Non-Diabetics: Associated Conditions and Possible Risk Factors. Gastroenterology Res. 2018 Oct;11(5):340-345 Authors: Nassar Y, Richter S Abstract Background: Gastroparesis is a syndrome characterized by delayed gastric emptying in the absence of any mechanical cause. While often associated with diabetes mellitus, most cases of gastroparesis are idiopathic. The purpose of the present paper is to review the co-morbid conditions that most likely associate with non-diabetic gastroparesis. Methods: The Healthcare Cost and Utilization Project: Nationwide Inpatient Sample (HCUP-NIS) data were used from the year 2013 - 2014 and the Apriori algorithm was run on this subset of patients to identify what co-morbid conditions are most likely associated with gastroparesis. Results: Notable conditions that were found to be most closely linked with gastroparesis were: chronic pancreatitis, end stage renal disease, irritable bowel syndrome, systemic lupus erythematosus, fibromyalgia, and venous thromboembolism. Some of the implications of these findings are briefly discussed. Conclusions: Gastroparesis is strongly associated with multiple medical conditions which may be potential targets for treatment. PMID: 30344804 [PubMed] View the full article

Pubmed-Initial Diagnosis of Functional Gastrointestinal Disorders in Children Increases a Chance for Resolution of Symptoms.

Oct 23, 2018
Related Articles Initial Diagnosis of Functional Gastrointestinal Disorders in Children Increases a Chance for Resolution of Symptoms. Pediatr Gastroenterol Hepatol Nutr. 2018 Oct;21(4):264-270 Authors: Trivić I, Hojsak I Abstract Purpose: The aim of this study was to describe functional gastrointestinal disorders (FGID) presented in a tertiary medical center, characteristics of patients and results of the diagnostic work-up together with an outcome during the follow up. Methods: This was a retrospective, single center, observational study including all patients who were diagnosed with FGID based on Rome III criteria from January to December 2015 in tertiary medical center. Results: Overall 294 children were included (mean age, 8.9 years [range, 1-18 years]; 165 females). Majority had functional constipation (35.4%), followed by functional abdominal pain (30.6%), irritable bowel syndrome (17.0%), functional dyspepsia (12.6%), functional nausea (3.4%) and abdominal migraine (1.0%). Regression model found that only significant factor associated with improvement of symptoms is the establishment of the functional diagnosis at the first visit (hazard ratio, 2.163; 95% confidence inverval, 1.029-4.544). There was no association between improvement of symptoms and presence of alarm signs/symptoms (weight loss, nocturnal symptoms and severe vomiting) at diagnosis. Furthermore, in pain symptoms (functional abdominal pain, irritable bowel syndrome, dyspepsia) no treatment positively correlated with pain improvement. Conclusion: Regardless of the initial diagnosis of FGID, positive diagnosis at the first visit increases a chance for resolution of symptoms. PMID: 30345239 [PubMed] View the full article

Pubmed-Circadian rhythms in the pathogenesis of gastrointestinal diseases.

Oct 23, 2018
Related Articles Circadian rhythms in the pathogenesis of gastrointestinal diseases. World J Gastroenterol. 2018 Oct 14;24(38):4297-4303 Authors: Codoñer-Franch P, Gombert M Abstract The etiology of digestive pathologies such as irritable bowel syndrome (IBS), inflammatory bowel diseases (IBD) and cancer is not yet fully understood. In recent years, several studies have evidenced circadian variations in mechanisms involved in digestive health. In situations of disturbed circadian rhythms (chronodisruption) where the central clock and the peripheral clocks receive incoherent signals, the synchronicity is lost producing implications for health. This lack of coordination could alter the tissue function and cause long term damage to the organs. Life habits such as sleep, physical exercise, social interaction, and feeding times are determinants for stability and integrity of circadian rhythms. In recent years, experimental and clinical studies have consistently evidenced that the alteration of circadian rhythms is associated with the development of digestive pathologies mainly linked to dismotility or changes in microbiota composition. Likewise, it seems reasonable to deep into the importance of chronodisruption as a factor that may participate in the development of pathologies such as IBS, IBD and digestive cancers. Moreover, life habits respecting circadian rhythms should be promoted for the prevention of these diseases. Further studies will allow us a better understanding of the mechanisms acting at molecular level, and the development of new therapeutic targets. PMID: 30344415 [PubMed - in process] View the full article

Twitter-RT @NatRevGastroHep: Are 'functional' GI disorders truly functional? Nathalie Vergnolle discusses the pathways regulating visceral pain #UE…

Oct 23, 2018
RT @NatRevGastroHep: Are 'functional' GI disorders truly functional? Nathalie Vergnolle discusses the pathways regulating visceral pain #UE… (RSS generated with FetchRss) View the full article

Twitter-RT @hmstaudacher: Fascinating talk by Fergus Shanahan on selecting microbiota for interventions. Context trumps it all #uegweek https://t.c…

Oct 23, 2018
RT @hmstaudacher: Fascinating talk by Fergus Shanahan on selecting microbiota for interventions. Context trumps it all #uegweek https://t.c… (RSS generated with FetchRss) View the full article

Twitter-RT @martatejedor4: Presenting our innovative experience in #IBS at #UEGWeek!!! @HUInfantaElena https://t.co/H4LXtYSuzZ

Oct 23, 2018
RT @martatejedor4: Presenting our innovative experience in #IBS at #UEGWeek!!! @HUInfantaElena (RSS generated with FetchRss) View the full article

Google-Vibrating capsule effective for chronic idiopathic constipation

Oct 22, 2018
Vibrating capsule effective for chronic idiopathic constipation Healio Full coverage View the full article

Google-Home-based biofeedback therapy is effective option for tough-to-treat constipation

Oct 22, 2018
Home-based biofeedback therapy is effective option for tough-to-treat constipation EurekAlert (press release) Full coverage View the full article

Twitter-RT @robinberlinrd: The use of Probiotics: Possible dangers vs benefits. Bottom line-More info and research is needed and the effect on our…

Oct 21, 2018
RT @robinberlinrd: The use of Probiotics: Possible dangers vs benefits. Bottom line-More info and research is needed and the effect on our… (RSS generated with FetchRss) View the full article

Twitter-RT @melissarvh: #IBS – 4 symptoms that extend beyond your stomach https://t.co/0YjPdNC3iW via @health24com @IFFGD @gimotility

Oct 21, 2018
RT @melissarvh: #IBS – 4 symptoms that extend beyond your stomach https://www.health24.com/Medical/IBS/About-IBS/ibs-4-symptoms-that-extend-beyond-your-stomach-20181019 via @health24com @IFFGD @gimotility (RSS generated with FetchRss) View the full article

Pubmed-Τ Eluxadoline for IBS-D.

Oct 20, 2018
Related Articles Τ Eluxadoline for IBS-D. Drug Ther Bull. 2017 Aug;55(8):91-92 Authors: PMID: 28808082 [PubMed - indexed for MEDLINE] View the full article

Pubmed-Update on Dietary Management of Childhood Functional Abdominal Pain Disorders.

Oct 20, 2018
Related Articles Update on Dietary Management of Childhood Functional Abdominal Pain Disorders. Gastroenterol Clin North Am. 2018 Dec;47(4):715-726 Authors: Chumpitazi BP Abstract Diet plays a significant role for children with functional abdominal pain disorders. A large majority of these children identify at least 1 food that exacerbates their symptoms. Malabsorbed carbohydrates may have both direct and microbiome-mediated physiologic effects. There are several factors associated with carbohydrate symptom generation, including (1) the amount ingested, (2) ingestion with a meal, (3) small intestinal enzymatic activity, (4) consuming the carbohydrate with microorganisms capable of breaking down the carbohydrate, (5) the gut microbiome, and (6) host factors. Therapies include carbohydrate (single and/or comprehensive) restriction, selective prebiotic and/or enzyme supplementation. Fiber supplementation may also be beneficial. PMID: 30337028 [PubMed - in process] View the full article

Pubmed-Brain-Gut Axis: Clinical Implications.

Oct 20, 2018
Related Articles Brain-Gut Axis: Clinical Implications. Gastroenterol Clin North Am. 2018 Dec;47(4):727-739 Authors: Khlevner J, Park Y, Margolis KG Abstract This article provides an overarching view of what is currently known about the physiology of the brain-gut axis in both health and disease and how these concepts apply to irritable bowel syndrome, the most common functional gastrointestinal disorder in pediatrics. PMID: 30337029 [PubMed - in process] View the full article

Pubmed-Integration of Biomedical and Psychosocial Treatments in Pediatrics Functional Gastrointestinal Disorders.

Oct 20, 2018
Related Articles Integration of Biomedical and Psychosocial Treatments in Pediatrics Functional Gastrointestinal Disorders. Gastroenterol Clin North Am. 2018 Dec;47(4):863-875 Authors: van Tilburg MAL, Carter CA Abstract Pediatric functional gastrointestinal disorders (FGIDs) are disorders of the brain-gut axis. Pathophysiological factors include alterations in gut motility, microbiota, immune system, central nervous system, and psychosocial factors. Given the complex pathophysiology of FGIDs, many patients are in need of integrative treatment approaches that may include a combination of biomedical, nutritional, and psychological approaches. In this article, we examine goals of treatment; give a brief overview of biomedical, nutritional, and psychological approaches; and finally discuss the integrative management of pediatric FGIDs. PMID: 30337037 [PubMed - in process] View the full article

Pubmed-Is body mass index associated with symptom severity and health-related quality of life in irritable bowel syndrome? A cross-sectional study.

Oct 20, 2018
Related Articles Is body mass index associated with symptom severity and health-related quality of life in irritable bowel syndrome? A cross-sectional study. BMJ Open. 2018 Oct 17;8(10):e019453 Authors: Dong Y, Berens S, Eich W, Schaefert R, Tesarz J Abstract OBJECTIVE: The aim of this study was to describe the body mass index (BMI) distribution in patients with irritable bowel syndrome (IBS) based on the Rome III criteria and to evaluate the association of BMI with symptom severity and quality of life (QOL). METHODS: A cross-sectional study was carried out in patients visiting our outpatient functional gastrointestinal disorders specialty clinic. IBS diagnosis was made based on Rome III criteria. IBS symptom severity was investigated using the IBS severity score system. QOL was assessed using the Short Form 36 Health Survey, which consists of physical health and mental health. RESULTS: 366 patients (252 women) who fulfilled Rome III criteria and provided complete BMI data (23.90±5.22 kg/m2) were included. Overall, 59.0% of patients with IBS were in the normal weight range, 30.3% were overweight or obese, and 10.7% were underweight. Both physical and mental health decreased significantly with the severity of symptoms (all p<0.01), while controlling for several covariates (age, gender, family status, education status and IBS subtypes). Obesity and symptom severity (β=-0.177,△R2=0.037, p<0.01; β=-0.387,△R2=0.147, p<0.01) were significant negative factors that influencing physical health. Symptom severity (β=-0.301,△R2=0.084, p<0.01) was significant negative factor that influencing mental health. However, BMI didn't account for additional variance in mental health (p>0.05). CONCLUSION: Being overweight is a common phenomenon in patients with IBS regardless of IBS subtype. The association between QOL and symptom severity followed a negative dose-response pattern. Patients with higher BMI, especially obese patients, were more frequently in poor physical health. However, this kind of relationship was not found in BMI and mental health. PMID: 30337304 [PubMed - in process] View the full article

Twitter-no. 46 - The Probiotics and Prebiotics Episode https://t.co/r6mGAXXthW

Oct 19, 2018
no. 46 - The Probiotics and Prebiotics Episode https://thisunmillenniallife.com/benefits-of-probiotics-and-prebiotics/ (RSS generated with FetchRss) View the full article

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