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Brand Name Generic namesort descending IBS type Type Comments
Visbiome® 8 strains of lactic acid bacteria All IBS types Over-the-counter Probiotic medical food is designated for the dietary management of IBS. It is a prescribable medicine and should not be confused with an over-the-counter probiotic. It must be used under medical supervision and may be dispensed by a pharmacist.
Lotronex® alosetron IBS-D Prescription For some women with severe irritable bowel syndrome (IBS) whose main problem is diarrhea; whose IBS symptoms have lasted 6 months or longer and have not been helped enough by other treatments.
Viberzi® / Truberzi® eluxadoline IBS-D Prescription Used to treat men and women adults who have irritable bowel syndrome with diarrhea (IBS-D). Truberzi® was recently approved for use in the European Union.
Trulance® / Plecanatide® guanylate cyclase-C agonist IBS-C Prescription Stimulate digestive fluid movement and support regular bowel function. Trulance (plecanatide) is approved for the treatment of IBS-C and Chronic Idiopathic Constipation (CIC) in adult patients in the United States.
Linzess® / Constella® linaclotide IBS-C Prescription To treat irritable bowel syndrome with constipation (IBS‑C) and chronic idiopathic constipation (CIC).
Amitiza® lubiprostone IBS-C Prescription indicated for IBS-C or chronic idiopathic constipation
Dicetel® pinaverium bromide All IBS types Prescription For the treatment and relief of symptoms associated with irritable bowel syndrome (IBS): abdominal pain, bowel disturbances and intestinal discomfort.
Resotran® / Motegrity® prucalopride IBS-C Prescription Prokinetic agent that works by targeting the serotonin (5-HT4) receptors in the intestines. Used for the treatment of chronic idiopathic constipation in women for whom laxative treatment has failed to provide relief by stimulating the muscle movement. Resotran™ and Motegrity™ are only approved in the Canada and the US respectively for chronic idiopathic constipation (CIC).
Xifaxan® / Zaxine® / Xifaxnta® / Xifapil® / Ciboz® rifaximin IBS-D Prescription Antibiotic indicated for the treatment of irritable bowel syndrome with diarrhea (IBS-D) in adults.
EnteraGam® serum-derived bovine immunoglobulin/protein isolate IBS-D Prescription Medical food for chronic loose or frequent stools (IBS-D).
IBgard® Ultramen®, an ultra-purified peppermint oil All IBS types Over-the-counter Targeted technology to deliver peppermint oil directly to the small intestine